Angel - Her Dad, James, had a good heart. He tried to raise her right, but had no clue the Overseer would go batshit insane after he managed to escape. He died trying to keep her safe. She destroyed Raven's Rock in retaliation.

Elisa - Probably the only one with a decent family, ngl. IIRC, her dad was an NYPD cop as well.

Lady - We don't talk about Arkham. Or how she put a bullet in his head after Dante beat the snot out of him

Makoto Niijima - Good dad, was a cop.

Riza Hawkeye - Her dad is the reason for the ink and scars on her back. He is also the reason she met Roy.