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SARS-CoV-2 infection and persistence in the human bo..."SARS-CoV-2 is widely distributed, predominantly among patients who died with severe COVID-19, and that virus replication is present in multiple respiratory and non-respiratory tissues, including the brain, early in infection"#long-COVID #SARS-CoV-2
"Despite extensive distribution of SARS-CoV-2 RNA throughout the body, we observed little evidence of inflammation or direct viral cytopathology outside the respiratory tract. Our data indicate that in some patients SARS-CoV-2 can cause systemic infection and persist in the body for months."
"We carried out quantitative real-time PCR with reverse transcription (RT–qPCR) to detect subgenomic RNA, a marker suggestive of recent virus replication15, and demonstrated replication-competent SARS-CoV-2 in selected respiratory and non-respiratory tissues, including the brain, by virus isolation in traditional and modified Vero E6 cell culture."
